Description

5-Bromothiophen-2(5H)-One is a versatile brominated heterocyclic building block with significant synthetic utility. This compound is valued for its reactivity as an electrophilic synthon, enabling the construction of complex thiophene-based molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for use in organic synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized thiophene cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the thiophene moiety imparts specific biological activity.
• Material Science Research: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials like OLEDs and semiconductors.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as a substrate for nucleophilic substitution to introduce diverse functional groups.
• Ligand and Catalyst Development: Useful for constructing novel heterocyclic ligands for metal complexes used in catalysis.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	5-Bromothiophen-2(5H)-One
CAS No.	17019-33-9
Molecular Formula	C4H3BrOS
Molecular Weight	179.03 g/mol
Synonyms	5-Bromothiophen-2(5H)-one; 2(5H)-Thiophenone, 5-bromo-; 5-Bromo-2(5H)-thiophenone; 5-Bromo-2,5-dihydrothiophen-2-one; 5-Bromothiophen-2-one; 5-Bromo-2-thiophenone; 5-Bromodihydrothiophen-2(3H)-one
EINECS	Contact for details

Quality Control

Our 5-Bromothiophen-2(5H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.