Description

(S)-4-Isobutyl-2-Oxazolidinone is a high-value, enantiomerically pure chiral auxiliary and building block in organic synthesis. Its significance lies in its ability to induce stereoselectivity in a wide range of chemical transformations, enabling the production of single-isomer pharmaceutical intermediates and fine chemicals. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over molecular chirality.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Widely used to control stereochemistry in aldol, alkylation, and Diels-Alder reactions.
• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in routes requiring the (S)-configuration.
• Agrochemical Synthesis: Employed in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Catalyst and Ligand Preparation: Serves as a precursor for novel chiral catalysts and ligands used in homogeneous catalysis.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances where specific stereochemistry is critical.
• Academic and Industrial R&D: A fundamental reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	(S)-4-Isobutyl-2-Oxazolidinone
CAS No.	17016-85-2
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(S)-(-)-4-Isobutyl-2-oxazolidinone; (4S)-4-(2-Methylpropyl)-1,3-oxazolidin-2-one; (S)-4-(2-Methylpropyl)-2-oxazolidinone; (S)-N-Isobutyloxycarbonyl-2-amino-2-methylpropanol cyclic derivative; Evans Auxiliary derivative; Chiral oxazolidinone auxiliary
EINECS	Contact for details

Quality Control

Our (S)-4-Isobutyl-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for asymmetric synthesis and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.