Description

3-Chloro-1-Methyl-5,6,7,8-Tetrahydroisoquinoline-4-Carbonitrile is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring a tetrahydroisoquinoline core with chloro and nitrile substituents, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with potentially novel modes of action.
• Material Science: Used in the research and development of advanced organic materials, including ligands for catalysts and components for organic electronics.
• Chemical Synthesis: Employed in academic and industrial laboratories for methodological studies and the construction of complex nitrogen-containing heterocycles.
• Bioconjugation & Probe Development: The reactive chloro and nitrile groups can be utilized for attaching fluorophores or other tags in biochemical probe synthesis.

Basic Information

Product Name	3-Chloro-1-Methyl-5,6,7,8-Tetrahydroisoquinoline-4-Carbonitrile
CAS No.	17012-31-6
Molecular Formula	C11H11ClN2
Molecular Weight	206.67 g/mol
Synonyms	3-Chloro-1-methyl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile; 4-Cyano-3-chloro-1-methyl-5,6,7,8-tetrahydroisoquinoline; 1-Methyl-3-chloro-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile; 3-Chloro-1-methyl-1,2,3,4-tetrahydroisoquinoline-4-carbonitrile; 17012-31-6; Tetrahydroisoquinoline-4-carbonitrile derivative
EINECS	Contact for details

Quality Control

Our 3-Chloro-1-Methyl-5,6,7,8-Tetrahydroisoquinoline-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.