Description

(1S,2S)-(+)-2-Amino-1-[4-(Methylthio)Phenyl]-1,3-Propanediol is a high-purity chiral amino diol building block of significant importance in asymmetric synthesis. Its value lies in its well-defined stereochemistry, which is critical for imparting specific biological activity and optical purity in final pharmaceutical compounds. This product is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing novel active pharmaceutical ingredients (APIs), particularly for applications in antiviral and cardiovascular therapies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, including protease inhibitors and other biologically active compounds.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for enantioselective reactions.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex molecular architectures with defined stereocenters in research and development.
• API Development: Critical for the research and scale-up of new Active Pharmaceutical Ingredients (APIs) requiring high enantiomeric purity.
• Biochemical Research: Employed in studies involving enzyme inhibitors and receptor binding assays due to its specific stereochemistry.

Basic Information

Product Name	(1S,2S)-(+)-2-Amino-1-[4-(Methylthio)Phenyl]-1,3-Propanediol
CAS No.	16854-32-3
Molecular Formula	C10H15NO2S
Molecular Weight	213.30 g/mol
Synonyms	(+)-(1S,2S)-2-Amino-1-(4-methylthiophenyl)-1,3-propanediol; (1S,2S)-2-Amino-1-(4-(methylthio)phenyl)propane-1,3-diol; (1S,2S)-Amino Diol; D-threo-(+)-2-Amino-1-(p-methylthiophenyl)-1,3-propanediol; (1S,2S)-APD; (1S,2S)-2-Amino-1,3-propanediol derivative; 4-Methylthiophenyl amino diol
EINECS	Contact for details

Quality Control

Our (1S,2S)-(+)-2-Amino-1-[4-(Methylthio)Phenyl]-1,3-Propanediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with full specification data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.