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N,n-Dimethylacetamide-D9 CAS NO 16727-10-9


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CAS No.:16727-10-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N,n-Dimethylacetamide-D9 is a deuterated analog of the common polar aprotic solvent N,N-Dimethylacetamide (DMAc), where all nine hydrogen atoms are replaced by deuterium. This isotopic labeling makes it an essential tool in advanced research and analytical chemistry, particularly for nuclear magnetic resonance (NMR) spectroscopy. It is primarily used by pharmaceutical, agrochemical, and academic research laboratories as a non-reactive, deuterated solvent for structural elucidation and reaction mechanism studies.

Application

  • NMR Spectroscopy Solvent: A critical deuterated solvent for proton NMR, providing a non-interfering signal background for analyzing organic compounds and polymers.
  • Pharmaceutical Research: Used in the synthesis and analysis of deuterated drug molecules and active pharmaceutical ingredients (APIs) for metabolic and pharmacokinetic studies.
  • Polymer Chemistry: Serves as a solvent for characterizing synthetic polymers and plastics via NMR techniques.
  • Reaction Mechanism Studies: Employed as a deuterium source or inert solvent in mechanistic investigations to track hydrogen/deuterium exchange.
  • Analytical Chemistry: Used as a mobile phase component or sample solvent in LC-MS and other hyphenated analytical techniques.
  • Agrochemical Development: Utilized in the research and analysis of novel, isotopically labeled pesticides and herbicides.

Basic Information

Product Name N,n-Dimethylacetamide-D9
CAS No. 16727-10-9
Molecular Formula C4D9NO
Molecular Weight 91.17 g/mol (deuterated form)
Synonyms Deuterated DMAc; DMAc-d9; N,N-Dimethylacetamide-d9; Acetamide-D9, N,N-dimethyl-; (Trideuteroacetyl)bis(trideuteromethyl)amine; Perdeuterated N,N-Dimethylacetamide; Deuterated Dimethylacetamide; NMR Solvent DMAc-d9
EINECS Contact for details

Quality Control

Our N,n-Dimethylacetamide-D9 is produced and handled under strict quality management protocols to ensure the highest isotopic and chemical purity for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D atom %), chemical assay, water content, and NMR spectral data. We ensure compliance with relevant standards for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent absorption of atmospheric moisture and degradation.

Specification

Item Specification
Appearance Colorless clear liquid
Identification (IR) Conforms
Assay (GC) ≥ 99.0%
Isotopic Purity (D atom %) ≥ 99.5%
Water Content (KF) ≤ 0.1%
NMR Solvent Suitability Passes test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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