Description

1,2:3,4-Di-o-Isopropylidene-6-Thio-A-D-Galactopyranose is a high-purity, protected thiogalactose derivative, serving as a critical chiral building block and synthetic intermediate. Its value lies in providing a chemically stable scaffold for the controlled introduction of sulfur functionalities into complex molecular architectures. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating nucleoside analogs, glycoconjugates, and carbohydrate-based active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer research.
• Glycochemistry & Glycobiology: Used in the preparation of thioglycosides and other sulfur-containing carbohydrate mimics for studying biological recognition processes.
• API Synthesis: Serves as a chiral starting material or advanced intermediate in the multi-step synthesis of complex carbohydrate-based active pharmaceutical ingredients.
• Chemical Biology Probes: Enables the development of labeled or modified sugar analogs used as tools to investigate enzymatic pathways and cellular mechanisms.
• Material Science Research: Potential monomer or precursor for synthesizing specialized polymers with unique properties derived from the sugar backbone.

Basic Information

Product Name	1,2:3,4-Di-o-Isopropylidene-6-Thio-A-D-Galactopyranose
CAS No.	16714-07-1
Molecular Formula	C₁₂H₂₀O₅S
Molecular Weight	276.35 g/mol
Synonyms	6-Thio-1,2:3,4-di-O-isopropylidene-α-D-galactopyranose; 6-Thio-di-O-isopropylidene-D-galactose; 1,2:3,4-Di-O-isopropylidene-6-thio-α-D-galactopyranose; 6-Thio-1,2:3,4-di-O-isopropylidene-D-galactopyranose; 6-Thio-di-O-isopropylidene-α-D-galactopyranose; 6-Deoxy-6-thio-1,2:3,4-di-O-isopropylidene-α-D-galactopyranose; D-Galactose, 6-deoxy-6-thio-, 1,2:3,4-diisopropylidene acetal
EINECS	240-777-5

Quality Control

Our 1,2:3,4-Di-o-Isopropylidene-6-Thio-A-D-Galactopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity (typically by HPLC), specific rotation, and other critical parameters are provided to guarantee batch-to-batch consistency and suitability for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]²⁰D	-80° to -90° (c=1 in CHCl₃)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.