Description

2-Amino-4-Hydroxy-3-Thiophenecarboxylic Acid Ethyl Ester is a versatile heterocyclic building block of significant importance in synthetic organic chemistry. Its core value lies in its multifunctional structure, which allows for the construction of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily needed by research chemists and process development scientists for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of thiophene-based drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that leverage the thiophene scaffold for bioactivity.
• Material Science: Serves as a monomer or building block for the development of specialty polymers and organic electronic materials.
• Dye & Pigment Synthesis: Employed in the creation of heterocyclic dyes and functional colorants.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new chemical spaces in university and CRO laboratories.
• Custom Synthesis: Used by fine chemical manufacturers for the bespoke production of complex molecules for client projects.

Basic Information

Product Name	2-Amino-4-Hydroxy-3-Thiophenecarboxylic Acid Ethyl Ester
CAS No.	16694-23-8
Molecular Formula	C7H9NO3S
Molecular Weight	187.22 g/mol
Synonyms	Ethyl 2-Amino-4-hydroxy-3-thiophenecarboxylate; 2-Amino-4-hydroxy-thiophene-3-carboxylic acid ethyl ester; 4-Hydroxy-2-aminothiophene-3-carboxylic acid ethyl ester; 3-Thiophenecarboxylic acid, 2-amino-4-hydroxy-, ethyl ester; Ethyl 2-amino-4-hydroxythiophene-3-carboxylate; 2-Amino-4-hydroxy-3-carbethoxythiophene; 3-Carbethoxy-2-amino-4-hydroxythiophene
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Hydroxy-3-Thiophenecarboxylic Acid Ethyl Ester is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity building blocks for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.