Description

Trimethyl-D6-Amine (Dimethyl-D6) is a deuterated analog of trimethylamine, where all six hydrogen atoms on the three methyl groups are replaced by deuterium (²H or D). This high isotopic purity makes it an essential internal standard and labeling reagent in analytical chemistry and advanced material synthesis. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical instrumentation sectors for applications requiring precise molecular tracking and minimal background interference.

Application

• NMR Spectroscopy Internal Standard: Provides a deuterium lock signal and chemical shift reference in deuterated solvents for high-resolution nuclear magnetic resonance analysis.
• Mass Spectrometry (MS) & LC-MS: Serves as a critical internal standard for the accurate quantification of trimethylamine and related compounds using isotope dilution mass spectrometry techniques.
• Pharmaceutical Research & Metabolism Studies: Used as a stable isotope-labeled tracer to study the metabolic pathways, pharmacokinetics, and degradation products of drug candidates and bioactive amines.
• Deuterated Chemical Synthesis: Acts as a key building block for introducing deuterium labels into more complex organic molecules, enhancing their stability or analytical properties.
• Environmental & Food Safety Testing: Employed in analytical methods to detect and quantify trace levels of trimethylamine, a marker for spoilage and environmental contamination.
• Material Science: Utilized in the synthesis of specialized deuterated polymers or surface-modifying agents for research in neutron scattering studies.

Basic Information

Product Name	Trimethyl-D6-Amine (Dimethyl-D6)
CAS No.	16585-35-6
Molecular Formula	C₃D₉N
Molecular Weight	68.15 g/mol
Synonyms	Perdeuterated Trimethylamine; Trimethylamine-d9; TMA-d9; N,N-Dimethyl(methyl-d3)-amine-d6; (²H₉)Trimethylamine; Deuterated Trimethylamine; N(CD₃)₃; 2,2,2-Trideuterio-N,N-bis(trideuteriomethyl)methanamine
EINECS	Contact for details

Quality Control

Our Trimethyl-D6-Amine is produced and handled under strict quality protocols to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D atom %), chemical purity by GC or NMR, and solvent residues. We adhere to cGMP principles for laboratory chemicals, ensuring traceability and consistency for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and strong alkaline/organic solvent nature, store in a cool (15-25°C), well-ventilated area away from heat, sparks, and open flames. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Store separately from strong acids and oxidizers.

Specification

Item	Specification
Appearance	Colorless liquid
Identification (IR / NMR)	Conforms to structure
Isotopic Purity (D atom %)	≥ 99%
Chemical Purity (GC / NMR)	≥ 98%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.