Description

Trimethyl-D3-Amine (Methyl-D3) is a deuterated isotopologue of trimethylamine, where three hydrogen atoms are replaced by deuterium (²H or D). This compound is a critical stable isotope-labeled building block for advanced research and analytical applications, offering a non-radioactive tracer with distinct mass spectral properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for applications such as internal standards, metabolic studies, and mechanistic investigations.

Application

• As an internal standard for the accurate quantification of trimethylamine and related metabolites in complex biological matrices via GC-MS or LC-MS.
• A key deuterated precursor in the synthesis of labeled pharmaceuticals and agrochemicals for drug metabolism and pharmacokinetics (DMPK) studies.
• Used in NMR spectroscopy as a solvent or reagent for mechanistic studies, leveraging the absence of proton signals from the methyl groups.
• Essential in environmental and food science research for tracing the pathways and degradation products of trimethylamine.
• Employed in material science for the development of specialty polymers and surface-modifying agents where isotopic labeling is required.

Basic Information

Product Name	Trimethyl-D3-Amine (Methyl-D3)
CAS No.	16585-34-5
Molecular Formula	C₃D₉N
Molecular Weight	62.14 g/mol
Synonyms	Perdeuterotrimethylamine; Trimethylamine-d9; N,N-Dimethyl(methyl-d3)-amine; (2H9)Trimethylamine; TMA-d9; Deuterated Trimethylamine; N(CD3)3; Methyl-d3-amine (trimethyl-)
EINECS	Contact for details

Quality Control

Our Trimethyl-D3-Amine is produced and handled under strict quality protocols to ensure high isotopic and chemical purity, essential for sensitive analytical and synthetic work. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (D atom %), chemical purity by GC, and impurity profiles. We adhere to relevant industry standards for stable isotope-labeled compounds, and custom purity grades or specific analytical data packages are available to meet your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at 2-8°C. The container must be kept upright and securely sealed to prevent pressure build-up and loss of material. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless liquid
Identification (IR / NMR)	Conforms to structure
Isotopic Enrichment (D atom %)	≥ 98%
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.