Description

Bromomethyldimethylchlorosilane is a highly versatile organosilicon reagent featuring both bromomethyl and chlorosilyl functional groups. This bifunctional nature makes it a critical intermediate for introducing silyl-protecting groups and creating silicon-bridged molecular architectures. It is essential for researchers and manufacturers in advanced material science and fine chemical synthesis who require precise molecular modification. Its primary utility lies in serving as a key building block for silicon-containing polymers, surface modifiers, and specialized pharmaceutical intermediates.

Application

• Surface Modification Agent: Used to functionalize silica, glass, and other inorganic surfaces to alter wettability, adhesion, and reactivity.
• Polymer & Resin Synthesis: Acts as a monomer or cross-linking agent in the production of silicone resins and specialty polymers with tailored properties.
• Pharmaceutical Intermediates: Serves as a key synthon for introducing silicon into drug candidates, particularly in medicinal chemistry for probe and prodrug development.
• Protecting Group Chemistry: The chlorosilyl group is used to protect alcohols and other sensitive functionalities during multi-step organic syntheses.
• Adhesive & Sealant Formulations: Incorporated as an adhesion promoter and cross-linker in high-performance silicone-based adhesives and sealants.
• Chromatography Stationary Phases: Employed to derivatize silica gel for creating specialized HPLC and GC columns with specific separation selectivities.

Basic Information

Product Name	Bromomethyldimethylchlorosilane
CAS No.	16532-02-8
Molecular Formula	C3H8BrClSi
Molecular Weight	187.54 g/mol
Synonyms	Chloro(dimethyl)bromomethylsilane; (Bromomethyl)dimethylchlorosilane; Dimethyl(bromomethyl)chlorosilane; Bromomethyldimethylsilyl chloride; Silane, chlorodimethyl(bromomethyl)-; NSC 163081; (Bromomethyl)chlorodimethylsilane
EINECS	240-617-1

Quality Control

Our Bromomethyldimethylchlorosilane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, NMR, and titration to verify identity, potency, and impurity profiles. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality management system supports compliance with cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to minimize degradation and volatility. Keep away from heat, sparks, and open flame. Due to its moisture-sensitive and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening. Incompatible with strong bases, oxidizing agents, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Density (at 20°C)	1.30 - 1.35 g/mL
Refractive Index (n20D)	1.460 - 1.470
Related Impurities (GC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.