Description

Propanol-N, [1-14C] CAS NO 16504-75-9 is a carbon-14 labeled isotopologue of 1-propanol, where the radioactive isotope 14C is specifically incorporated at the first carbon position. This compound is an essential tool for precise metabolic and pharmacokinetic studies, enabling researchers to trace the fate of propanol and its derivatives in complex biological and chemical systems. It is primarily utilized by scientists and quality control professionals in the pharmaceutical, agrochemical, and advanced materials research sectors for applications requiring high-sensitivity detection and pathway elucidation.

Application

• Tracer Studies in Drug Metabolism and Pharmacokinetics (DMPK): Used to investigate the absorption, distribution, metabolism, and excretion (ADME) of propanol-based pharmaceutical compounds.
• Environmental Fate and Degradation Studies: Employed to track the breakdown pathways and persistence of propanol or related chemicals in environmental samples.
• Biochemical Pathway Analysis: Serves as a labeled precursor or intermediate in studying specific enzymatic reactions and metabolic pathways in vivo and in vitro.
• Chemical Reaction Mechanism Elucidation: Used in synthetic chemistry to determine reaction mechanisms and identify intermediates in catalytic or multi-step processes.
• Radiochemical Synthesis: Acts as a labeled building block for the synthesis of more complex carbon-14 labeled compounds for research and development.
• Quality Control and Method Development: Utilized as an internal standard or reference material in advanced analytical techniques like LC-MS for accurate quantification.

Basic Information

Product Name	Propanol-N, [1-14C]
CAS No.	16504-75-9
Molecular Formula	C14CH3CH2CH2OH / C3H8O (with 14C at C-1)
Molecular Weight	~62.10 g/mol (varies with specific activity)
Synonyms	1-Propanol-1-14C; n-Propanol-1-14C; [1-14C]Propan-1-ol; Propyl alcohol-1-14C; 1-Hydroxypropane-1-14C; Labeled 1-Propanol; Carbon-14 labeled n-propanol
EINECS	Contact for details

Quality Control

Every batch of Propanol-N, [1-14C] is produced and analyzed under strict quality systems to ensure identity, purity, and specific activity. Our products undergo rigorous quality testing to ensure compliance with industry standards for radiochemical purity and chemical purity. Certificates of Analysis (COA) detailing specific activity, radiochemical purity (by HPLC or TLC), chemical purity, and solvent composition are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures, typically between 2°C and 8°C (refrigerated) or as specified on the label, to maintain stability and minimize volatility. Due to its light-sensitive nature and high volatility, the container should be kept in a well-ventilated, dedicated radioactive materials storage area with appropriate shielding.

Specification

Item	Specification
Appearance	Colorless liquid
Identification (IR)	Conforms to structure
Specific Activity	Contact for details (mCi/mmol)
Radiochemical Purity (HPLC)	≥ 98%
Chemical Purity (GC)	≥ 98%
Solvent	Specified on COA (e.g., Ethanol, Water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.