Description

2-Iodo-3-Methylthiophene is a halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the construction of complex molecules, particularly in pharmaceutical and materials science research. Industries that need it include pharmaceutical R&D for active ingredient synthesis, agrochemical development, and the production of specialty chemicals and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing thiophene or iodinated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides where the thiophene ring system contributes to biological activity.
• Material Science Research: Serves as a monomer or building block for conductive polymers, organic semiconductors, and liquid crystals.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings for carbon-carbon bond formation.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new synthetic pathways.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands for metal complexes and catalysts.

Basic Information

Product Name	2-Iodo-3-Methylthiophene
CAS No.	16494-40-9
Molecular Formula	C5H5IS
Molecular Weight	224.06 g/mol
Synonyms	3-Methyl-2-iodothiophene; 2-Iodo-3-methylthiophene; 3-Methylthiophene-2-iodide; Iodo-3-methylthiophene; Thiophene, 2-iodo-3-methyl-; 2-Iodo-3-methyl-thiophene
EINECS	Contact for details

Quality Control

Our 2-Iodo-3-Methylthiophene is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopic methods, to verify identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.