Description

2-Iodo-5-Methylthiophene is a halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the construction of complex molecules, particularly in pharmaceutical and materials science research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as cross-coupling reactions and the synthesis of functionalized thiophene derivatives.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing functionalized thiophene cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage the thiophene scaffold.
• Material Science Precursor: Serves as a monomer or precursor in the development of conductive polymers, organic semiconductors, and advanced electronic materials.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings for carbon-carbon bond formation.
• Ligand and Catalyst Development: Utilized to create novel ligands for metal complexes and catalysts used in homogeneous catalysis.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial laboratories.

Basic Information

Product Name	2-Iodo-5-Methylthiophene
CAS No.	16494-36-3
Molecular Formula	C5H5IS
Molecular Weight	224.06 g/mol
Synonyms	5-Methyl-2-iodothiophene; 2-Iodo-5-methylthiophene; 5-Methylthiophene-2-iodide; Methyl-2-iodothiophene; Thiophene, 2-iodo-5-methyl-; Iodomethylthiophene; 2-Iodo-5-methyl-thiophene
EINECS	Contact for details

Quality Control

Our 2-Iodo-5-Methylthiophene is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.