Description

3-Iodo-2-Methylthiophene is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its reactivity, particularly in cross-coupling reactions, enabling the construction of complex molecular architectures. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry research targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the thiophene scaffold is a common bioactive moiety.
• Material Science & Organic Electronics: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Sonogashira couplings to form carbon-carbon bonds.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	3-Iodo-2-Methylthiophene
CAS No.	16494-34-1
Molecular Formula	C5H5IS
Molecular Weight	224.06 g/mol
Synonyms	2-Methyl-3-iodothiophene; 3-Iodo-2-methylthiophene; 2-Methyl-3-thienyl iodide; 3-Iodo-2-methyl-thiophene; Thiophene, 3-iodo-2-methyl-; Iodomethylthiophene
EINECS	Contact for details

Quality Control

Our 3-Iodo-2-Methylthiophene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production applications. We provide comprehensive analytical data, including purity assay and impurity profiling via techniques such as GC and HPLC. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.