Description

1-Bromo-2-Pentyne is a versatile alkyne halide building block, essential for advanced organic synthesis. Its reactive bromine and alkyne functional groups make it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as cross-coupling reactions and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and functional materials.
• Cross-Coupling Reactions: An effective substrate in Sonogashira, Heck, and other palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Organic Synthesis Reagent: Employed in laboratories for the introduction of pentynyl groups and for further functionalization via the alkyne moiety.
• Ligand and Catalyst Development: Useful in the preparation of novel ligands for catalysis and molecular recognition studies.

Basic Information

Product Name	1-Bromo-2-Pentyne
CAS No.	16400-32-1
Molecular Formula	C5H7Br
Molecular Weight	147.01 g/mol
Synonyms	2-Pentyn-1-yl Bromide; 2-Pentynyl Bromide; Bromo-2-pentyne; 1-Bromo-2-pentyne; 1-Bromo-pent-2-yne; Bromomethylbut-1-yne; (2-Pentynyl)bromide
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Pentyne is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as identity, assay, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flames. Containers must be kept tightly sealed when not in use to prevent evaporation and potential contamination.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Density (at 20°C)	~1.40 g/mL
Refractive Index (n20D)	~1.48

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.