Description

Ethyl 5-Methylindole-2-Carboxylate is a high-purity indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scalable synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new generation pesticides and plant growth regulators.
• Material Science: Serves as a precursor for organic semiconductors, dyes, and photochromic materials.
• Academic & Contract Research: Essential reagent in university and CRO laboratories for methodological studies and heterocyclic chemistry.
• Fine Chemical Synthesis: Intermediate for producing more complex indole-based compounds used in flavors, fragrances, and catalysts.

Basic Information

Product Name	Ethyl 5-Methylindole-2-Carboxylate
CAS No.	16382-15-3
Molecular Formula	C₁₂H₁₃NO₂
Molecular Weight	203.24 g/mol
Synonyms	5-Methyl-1H-indole-2-carboxylic acid ethyl ester; Ethyl 5-methyl-1H-indole-2-carboxylate; 2-Carbethoxy-5-methylindole; 5-Methylindole-2-carboxylic Acid Ethyl Ester; 1H-Indole-2-carboxylic acid, 5-methyl-, ethyl ester; Ethyl 5-methylindole-2-carboxylate; 5-Methyl-2-indolecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Methylindole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.