Description

[S(R*,R*)]-1-Phenylglycerol CAS NO 16354-95-3 is a high-purity, single-enantiomer chiral building block of significant importance in asymmetric synthesis. This compound is valued for its rigid phenyl-substituted glycerol backbone, which serves as a versatile precursor for constructing complex pharmaceutical intermediates and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of β-blockers, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Asymmetric Catalyst Ligand Precursor: Used to develop novel chiral ligands for transition metal catalysis in enantioselective reactions.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial Research: A valuable tool in medicinal chemistry and process development for exploring new synthetic pathways.
• Polymer Modification: Can be incorporated into polymer chains to impart specific chiral or functional properties to advanced materials.

Basic Information

Product Name	[S(R*,R*)]-1-Phenylglycerol
CAS No.	16354-95-3
Molecular Formula	C9H12O3
Molecular Weight	168.19 g/mol
Synonyms	(S,S)-1-Phenylglycerol; (S,S)-1-Phenyl-1,2,3-propanetriol; (S,S)-3-Phenyl-1,2-propanediol, 1-hydroxy derivative; (1S,2S)-1-Phenyl-1,2,3-propanetriol; (S,S)-Phenylglycerol; 1-Phenylglycerol (S,S)-isomer; α-Phenylglycerol (S,S)-form; L-threo-1-Phenylglycerol
EINECS	Contact for details

Quality Control

Our [S(R*,R*)]-1-Phenylglycerol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.