Description

3-Methyl-3H-diazirine-3-propanol is a specialized heterocyclic compound featuring a highly reactive diazirine ring. This compound matters as a versatile photoactivatable crosslinking agent and chemical probe in advanced research and development. It is primarily needed by researchers and manufacturers in the fields of bioconjugation, proteomics, and materials science for labeling and studying biomolecular interactions.

Application

• Photoaffinity Labeling: Used to create covalent bonds between biomolecules (e.g., proteins, nucleic acids) and their ligands upon UV light activation for interaction mapping.
• Bioconjugation Reagent: Serves as a key intermediate for synthesizing photo-crosslinkers to attach reporter molecules (fluorophores, biotin) to target molecules.
• Proteomics Research: Employed in identifying transient or weak protein-protein and protein-small molecule interactions within complex biological systems.
• Polymer & Materials Science: Acts as a crosslinking moiety to modify polymer surfaces or create photo-responsive materials and hydrogels.
• Pharmaceutical Development: Utilized in drug discovery for target identification and validation studies of novel therapeutic compounds.
• Chemical Biology Tool: Integrated into probe molecules to study enzyme active sites, receptor binding pockets, and other biological mechanisms.

Basic Information

Product Name	3-Methyl-3H-diazirine-3-propanol
CAS No.	16297-94-2
Molecular Formula	C5H10N2O
Molecular Weight	114.15 g/mol
Synonyms	3-(3-Methyl-3H-diazirin-3-yl)propan-1-ol; 3-(Diazirin-3-yl)propanol, 3-methyl-; 3-Methyl-3H-diazirine-3-propan-1-ol; 3-(3-Methyldiazirin-3-yl)-1-propanol; Diazirine-3-propanol, 3-methyl-; Photoactivatable crosslinker precursor; Diazirine alcohol derivative
EINECS	Contact for details

Quality Control

Our 3-Methyl-3H-diazirine-3-propanol is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to maintain stability and minimize volatility. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.