Description

5-Chloro-1-Benzothiophene-3-Carbonitrile is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers in fine chemical, pharmaceutical R&D, and material science industries seeking to develop novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and other functional organic materials due to its electron-withdrawing nitrile group and fused ring system.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the benzothiophene core imparts specific color and stability properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, cyclizations, and as a scaffold for constructing more complex polycyclic structures in academic and industrial research.

Basic Information

Product Name	5-Chloro-1-Benzothiophene-3-Carbonitrile
CAS No.	16296-79-0
Molecular Formula	C9H4ClNS
Molecular Weight	193.65 g/mol
Synonyms	5-Chlorobenzo[b]thiophene-3-carbonitrile; 5-Chloro-3-cyanobenzo[b]thiophene; 5-Chloro-1-benzothiophene-3-carbonitrile; 5-Chloro-benzo[b]thiophene-3-carbonitrile; 3-Cyano-5-chlorobenzo[b]thiophene; Benzo[b]thiophene-3-carbonitrile, 5-chloro-; 16296-79-0
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-Benzothiophene-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.