Description

4-Bromo-3-Phenylisothiazole is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its ability to act as a key intermediate for constructing complex molecules, particularly in the development of pharmaceuticals and agrochemicals. This compound is essential for research chemists and process development scientists working in medicinal chemistry, crop protection, and materials science, where it serves as a precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the isothiazole moiety's bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis, enabling novel synthetic transformations.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects requiring brominated aromatic heterocycles.

Basic Information

Product Name	4-Bromo-3-Phenylisothiazole
CAS No.	16187-94-3
Molecular Formula	C9H6BrNS
Molecular Weight	240.12 g/mol
Synonyms	3-Phenyl-4-bromoisothiazole; 4-Bromo-3-phenyl-1,2-thiazole; Isothiazole, 4-bromo-3-phenyl-; 4-Bromo-3-phenyl-δ²-isothiazoline; 16187-94-3; 4-Br-3-Ph-isothiazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Phenylisothiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.