Description

1-Methylindole-2-Carboxylic Acid is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its indole scaffold, which is a privileged structure in medicinal chemistry, enabling the development of novel pharmacologically active compounds. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in developing novel fungicides, herbicides, and plant growth regulators that leverage the biological activity of the indole moiety.
• Material Science: Serves as a building block for organic semiconductors, dyes, and photoactive materials due to its conjugated aromatic system.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocyclic compound library synthesis.
• Biochemical Probe Development: Utilized in creating molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	1-Methylindole-2-Carboxylic Acid
CAS No.	16136-58-6
Molecular Formula	C10H9NO2
Molecular Weight	175.18 g/mol
Synonyms	1-Methyl-1H-indole-2-carboxylic acid; 2-Carboxy-1-methylindole; 1-Methylindole-2-carboxylate; 1-Methyl-2-indolecarboxylic acid; 1-Methyl-2-carboxyindole; 2-(1-Methylindole)carboxylic acid; 1-Methyl-1H-indole-2-carboxylate; 1-Methylindol-2-carbonsäure (German)
EINECS	Contact for details

Quality Control

Our 1-Methylindole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.