Description

2,3,4,9-Tetrahydro-1-Methyl-1H-Pyrido[3,4-B]Indole-3-Carboxylic Acid Methyl Ester is a high-purity, synthetically derived heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its value lies in its complex fused-ring indole structure, which is a privileged scaffold for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This product is essential for research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex alkaloids and potential therapeutic agents targeting neurological and psychiatric disorders.
• Organic Synthesis Research: Used as a versatile precursor for constructing polycyclic frameworks in academic and industrial R&D laboratories.
• Agrochemical Development: Serves as an intermediate in the research and development of novel crop protection agents and pesticides.
• Fine Chemical Production: Employed in the manufacture of specialty dyes, pigments, and other high-value performance chemicals.
• Biochemical Probe Synthesis: Utilized to create molecular probes for studying biological pathways and enzyme interactions.

Basic Information

Product Name	2,3,4,9-Tetrahydro-1-Methyl-1H-Pyrido[3,4-B]Indole-3-Carboxylic Acid Methyl Ester
CAS No.	16108-10-4
Molecular Formula	C15H16N2O2
Molecular Weight	256.30 g/mol
Synonyms	1-Methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester; Methyl 1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate; 1-Methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester; Tetrahydroharmine methyl ester; 3-Carbomethoxy-1-methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole; THHME; 16108-10-4; Methyl tetrahydroharmine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 2,3,4,9-Tetrahydro-1-Methyl-1H-Pyrido[3,4-B]Indole-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.