Description

6-Bromo-5-Hydroxy-2-Methyl-1H-Indole-3-Arboxylic Acid, Ethyl Ester is a high-purity, functionalized indole derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to create novel compounds with specific biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole core.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and organic electronic materials.
• Biochemical Probe Synthesis: Employed in medicinal chemistry to create labeled compounds or probes for studying biological mechanisms.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting exploratory organic synthesis.
• Fine Chemical Production: Used in multi-step synthesis to produce high-value, complex organic molecules for various industrial applications.

Basic Information

Product Name	6-Bromo-5-Hydroxy-2-Methyl-1H-Indole-3-Arboxylic Acid, Ethyl Ester
CAS No.	16052-67-8
Molecular Formula	C₁₃H₁₄BrNO₃
Molecular Weight	312.16 g/mol
Synonyms	Ethyl 6-Bromo-5-hydroxy-2-methyl-1H-indole-3-carboxylate; 6-Bromo-5-hydroxy-2-methylindole-3-carboxylic acid ethyl ester; 1H-Indole-3-carboxylic acid, 6-bromo-5-hydroxy-2-methyl-, ethyl ester; 16052-67-8; Ethyl 6-bromo-5-hydroxy-2-methylindole-3-carboxylate; 6-Bromo-5-hydroxy-2-methyl-1H-indole-3-carboxylic acid ethyl ester; 2-Methyl-6-bromo-5-hydroxyindole-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Hydroxy-2-Methyl-1H-Indole-3-Arboxylic Acid, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.