Description

p-Xylene-2,3,5,6-D4 is a deuterated isotopologue of para-xylene, specifically labeled on the aromatic ring. This compound is a critical analytical standard and tracer used in advanced research and industrial quality control processes. It is essential for scientists and engineers in the pharmaceutical, polymer, and petrochemical industries who require precise internal standards for NMR spectroscopy, mass spectrometry, and reaction mechanism studies.

Application

• NMR Spectroscopy Solvent & Internal Standard: Provides a deuterium lock signal and serves as a chemical shift reference in proton NMR analysis of organic compounds.
• Mass Spectrometry Tracer: Used in quantitative MS and GC-MS methods for metabolic studies, pharmacokinetics, and environmental analysis due to its distinct mass shift.
• Mechanistic Reaction Studies: Employed to elucidate reaction pathways and kinetics in organic synthesis and catalysis research.
• Polymer Science Research: Acts as a labeled monomer or additive in the study of polymerization mechanisms and polymer microstructure.
• Deuterated Solvent Production: Serves as a precursor or intermediate in the synthesis of other deuterated solvents and fine chemicals.
• Quality Control & Method Development: Essential for developing and validating analytical methods in pharmaceutical and chemical manufacturing.

Basic Information

Product Name	p-Xylene-2,3,5,6-D4
CAS No.	16034-43-8
Molecular Formula	C8D4H6 or C8H6D4
Molecular Weight	110.18 g/mol
Synonyms	1,4-Dimethyl-2,3,5,6-tetradeuteriobenzene; p-Xylene-d4; [2,3,5,6-2H4]-p-Xylene; Deuteriobenzene, 1,4-dimethyl-2,3,5,6-tetradeutero-; Benzene-1,4-d4, 2,5-dimethyl-; p-Xylene (aromatic ring-d4); 2,3,5,6-Tetradeutero-1,4-dimethylbenzene
EINECS	Contact for details

Quality Control

Our p-Xylene-2,3,5,6-D4 is manufactured under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements for research and analytical applications. Each batch is analyzed by NMR, GC-MS, and other relevant spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (atom % D), chemical purity, and solvent residues is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and ignition points. Due to its highly volatile nature, ensure containers are securely sealed to prevent evaporation and concentration of vapors. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (NMR)	Conforms to structure
Isotopic Purity (Atom % D)	≥ 98% (on aromatic ring)
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.