Description

4-Iodobenzyl Bromide is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both iodine and bromine substituents, makes it a critical intermediate for constructing complex molecules through cross-coupling and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring iodobenzyl or benzyl bromide motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where its halogenated structure enables specific biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis, such as Suzuki-Miyaura and other cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and polymers where halogenated aromatic units are required.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.
• Custom Organic Synthesis: A fundamental building block for contract research organizations (CROs) and fine chemical companies performing bespoke synthesis for clients.

Basic Information

Product Name	4-Iodobenzyl Bromide
CAS No.	16004-15-2
Molecular Formula	C7H6BrI
Molecular Weight	296.93 g/mol
Synonyms	1-(Bromomethyl)-4-iodobenzene; p-Iodobenzyl Bromide; α-Bromo-4-iodotoluene; 4-Iodophenylmethyl Bromide; (4-Iodophenyl)methyl Bromide; Bromo(4-iodophenyl)methane; NSC 406908
EINECS	240-135-8

Quality Control

Our 4-Iodobenzyl Bromide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to verify identity and purity against established specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with customer requirements for research and production use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78°C - 82°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.