Description

8-Methylpsoralen is a high-purity, synthetic furanocoumarin derivative, a key intermediate in pharmaceutical and photochemistry research. Its primary commercial value lies in its role as a potent photosensitizer and a critical building block for synthesizing more complex psoralen analogs. This compound is essential for R&D and manufacturing in the pharmaceutical, cosmetic, and life science sectors, particularly for applications involving UV-A light activation.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of therapeutic agents for photochemotherapy (PUVA therapy) targeting skin conditions like psoriasis and vitiligo.
• Photobiology Research: Used as a standard photosensitizer in academic and industrial research to study DNA intercalation, cross-linking, and cellular responses to UVA light.
• Cosmetic Ingredient R&D: Investigated for potential use in controlled phototherapy formulations and as a model compound for studying skin-lightening or depigmentation mechanisms.
• Biochemical Probe: Employed to label and study nucleic acid structures and protein interactions due to its specific photoreactive properties.
• Material Science: Serves as a functional monomer or additive in developing light-responsive polymers and advanced materials.
• Reference Standard: Utilized as an analytical standard in HPLC and GC methods for quality control of related pharmaceutical products and natural extracts.

Basic Information

Product Name	8-Methylpsoralen
CAS No.	15912-88-6
Molecular Formula	C12H8O3
Molecular Weight	200.19 g/mol
Synonyms	8-MOP; 8-Methoxypsoralen (common misnomer); Xanthotoxin (Note: Xanthotoxin typically refers to 8-Methoxypsoralen, but 8-Methylpsoralen is a related analog); 8-Methylfuro[3,2-g]chromen-7-one; 8-Methyl-7H-furo[3,2-g][1]benzopyran-7-one; Psoralen, 8-methyl-; Bergapten analog
EINECS	Contact for details

Quality Control

Our 8-Methylpsoralen is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from HPLC, NMR, and MS, supporting its use in research and cGMP manufacturing environments. Specifications are designed to meet the stringent requirements of pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.