Description

L-Ethyl 1,2,3,4-Tetrahydroisoquinoline-3-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant intermediate in its stable salt form. This compound matters as a critical building block for the synthesis of complex bioactive molecules, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily needed by the pharmaceutical, agrochemical, and fine chemical industries for research, process development, and scale-up activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular systems.
• Organic Synthesis Building Block: Used in the construction of complex tetrahydroisoquinoline alkaloids and other nitrogen-containing heterocycles.
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides with specific biological activity.
• Catalyst and Ligand Development: Employed in the research and preparation of novel chiral catalysts and ligands for asymmetric synthesis.
• Academic and R&D Laboratories: Utilized in chemical research for methodological studies and the exploration of new synthetic pathways.
• Fine Chemical Production: Integrated into multi-step synthesis processes for the manufacture of specialty and performance chemicals.

Basic Information

Product Name	L-Ethyl 1,2,3,4-Tetrahydroisoquinoline-3-Carboxylate Hydrochloride
CAS No.	15912-56-8
Molecular Formula	C13H17NO2 • HCl
Molecular Weight	255.74 g/mol
Synonyms	(3S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid ethyl ester hydrochloride; L-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid ethyl ester hydrochloride; Ethyl (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride; (S)-Ethyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate HCl; L-TIQ-OEt•HCl; L-Ethyl TIQ-3-carboxylate hydrochloride; (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid ethyl ester monohydrochloride
EINECS	Contact for details

Quality Control

Our L-Ethyl 1,2,3,4-Tetrahydroisoquinoline-3-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.