Description

1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid Ethyl Ester is a versatile heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a critical chiral intermediate for the development of complex pharmaceutical molecules and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of drug candidates, particularly for central nervous system (CNS) agents, enzyme inhibitors, and other bioactive molecules.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its isoquinoline scaffold for biological activity.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds and specialty chemicals used in material science.
• Academic & R&D: Employed in university and industrial research laboratories for methodological studies in asymmetric synthesis and medicinal chemistry.
• Peptidomimetics: The carboxylic acid ethyl ester moiety makes it a valuable component in the design and synthesis of peptide analogs and mimetics.

Basic Information

Product Name	1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	15912-55-7
Molecular Formula	C₁₂H₁₅NO₂
Molecular Weight	205.25 g/mol
Synonyms	Ethyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate; Ethyl 1,2,3,4-tetrahydro-3-isoquinolinecarboxylate; 3-Carbethoxy-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid ethyl ester; THIQ-3-COOEt; Tic-Et; Ethyl tetrahydroisoquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.