Description

2,3-Dihydro-1H-Indole-6-Carboxylic Acid Hydrochloride is a versatile indole-based building block and intermediate of significant importance in advanced organic synthesis. Its core value lies in providing a functionalized indoline scaffold, which is a privileged structure in medicinal chemistry for developing bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in the development of novel therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of drug candidates targeting a wide range of diseases, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the indoline core.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic compounds and fine chemicals in research and development.
• Chemical Research: Employed in academic and industrial R&D for exploring new chemical reactions and synthesizing libraries of compounds for biological screening.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and functional dyes due to its conjugated indole structure.

Basic Information

Product Name	2,3-Dihydro-1H-Indole-6-Carboxylic Acid Hydrochloride
CAS No.	15861-37-7
Molecular Formula	C9H9NO2 · HCl
Molecular Weight	199.63 g/mol
Synonyms	6-Carboxy-2,3-dihydroindole hydrochloride; Indoline-6-carboxylic acid hydrochloride; 2,3-Dihydro-1H-indole-6-carboxylic acid HCl; 6-Indolinecarboxylic acid hydrochloride; 1,2,3,4-Tetrahydro-6-carboline-6-carboxylic acid hydrochloride (related); 15861-37-7; 6-Carboxyindoline HCl
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1H-Indole-6-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.