Description

5-Cyano-2,3-Dihydro-1H-Indole is a versatile heterocyclic organic compound featuring a cyano-substituted indoline core structure, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular framework makes it a valuable building block for constructing complex pharmacologically active molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the development of organic electronic materials, dyes, and pigments.
• Chemical Biology & Proteomics: Employed as a scaffold for designing molecular probes and enzyme inhibitors in biochemical research.
• Academic & Contract Research: A fundamental reagent for methodological development in organic synthesis and catalysis studies at research institutions and CROs.

Basic Information

Product Name	5-Cyano-2,3-Dihydro-1H-Indole
CAS No.	15861-23-1
Molecular Formula	C9H8N2
Molecular Weight	144.17 g/mol
Synonyms	5-Cyanoindoline; 1H-Indole-5-carbonitrile, 2,3-dihydro-; 2,3-Dihydro-1H-indole-5-carbonitrile; 5-Cyano-2,3-dihydroindole; Indoline-5-carbonitrile; 5-CN-indoline
EINECS	Contact for details

Quality Control

Our 5-Cyano-2,3-Dihydro-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.