Description

1-Tosyl-1H-Benzo[D]Imidazole is a high-value, protected heterocyclic building block widely used in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise functionalization of the imidazole core, a key pharmacophore in many active molecules. It serves as a versatile intermediate for the development of pharmaceuticals, agrochemicals, and specialty materials, where its tosyl group offers excellent stability and reactivity control during multi-step synthetic sequences.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition, antiviral activity, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating functional polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes and molecular tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name	1-Tosyl-1H-Benzo[D]Imidazole
CAS No.	15728-44-6
Molecular Formula	C₁₄H₁₂N₂O₂S
Molecular Weight	272.32 g/mol
Synonyms	1H-Benzimidazole, 1-[(4-methylphenyl)sulfonyl]-; 1-(p-Toluenesulfonyl)-1H-benzimidazole; 1-Tosylbenzimidazole; 1-Tosyl-1H-benzimidazole; Benzimidazole, 1-tosyl-; 1-(Tosyl)benzimidazole; 1-(4-Methylbenzenesulfonyl)-1H-1,3-benzodiazole; N-Tosylbenzimidazole
EINECS	Contact for details

Quality Control

Our 1-Tosyl-1H-Benzo[D]Imidazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.