Description

Sodium Borodeuteride is a versatile and isotopically labeled reagent, specifically the deuterated analog of sodium borohydride. Its core value lies in its role as a selective and mild reducing agent, particularly valuable for introducing deuterium atoms into organic molecules. This product is essential for researchers and manufacturers in pharmaceutical development, organic synthesis, and analytical chemistry, where precise isotopic labeling is required for metabolic studies, reaction mechanism elucidation, and the synthesis of deuterated compounds.

Application

• Deuterium Labeling in Pharmaceutical Intermediates: Used in the synthesis of deuterated active pharmaceutical ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Mechanistic Studies in Organic Chemistry: Employed as a tracer to investigate reaction pathways and mechanisms in reduction reactions.
• Synthesis of Deuterated Standards: Critical for producing internal standards used in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy.
• Selective Carbonyl Reduction: Reduces aldehydes and ketones to corresponding deuterated alcohols under mild conditions.
• Polymer Chemistry: Used in the modification and synthesis of specialty polymers requiring deuterium labeling for structural analysis.
• Academic and Industrial R&D: A key reagent in research laboratories for developing new synthetic methodologies involving isotopic labels.

Basic Information

Product Name	Sodium Borodeuteride
CAS No.	15681-89-7
Molecular Formula	NaBD4
Molecular Weight	41.88 g/mol
Synonyms	Sodium Tetradeuteroborate; Sodium Borohydride-d4; Sodium Tetrahydroborate-d4; Borate(1-), tetradeuterio-, sodium (1:1); NaBD4; Sodium Deuteroborohydride; Deuterated Sodium Borohydride; Sodium Borodeuteride (NaBD4)
EINECS	Contact for details

Quality Control

Our Sodium Borodeuteride is produced and handled under strict quality protocols to ensure high isotopic purity and chemical consistency, critical for sensitive research and synthesis applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D atom %), chemical purity, and moisture content. We adhere to rigorous in-house specifications to meet the demanding requirements of pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle and store the product under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition. Long-term storage in a freezer (-20°C) is advised for optimal shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or lumps
Identification (IR)	Conforms
Assay (NaBD4)	≥ 98.0 %
Isotopic Purity (D atom %)	≥ 98.0 %
Moisture (KF)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.