Description

(+)-6-(3-Chloro-2-Hydroxy-3-Methylbutyl)-5,7-Dimethoxycoumarin CAS NO 15575-50-5 is a high-purity, optically active coumarin derivative characterized by its specific chlorinated and hydroxylated side chain. This compound is valued for its role as a critical synthetic intermediate and reference standard in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and studying structure-activity relationships.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex molecular architectures.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in HPLC and LC-MS analysis within R&D and QC laboratories.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore the biological activity of modified coumarin scaffolds.
• Fine Chemical Synthesis: Acts as a precursor for synthesizing more complex, functionalized coumarin derivatives with potential applications in material science or as specialty chemicals.
• Biochemical Probe: Utilized in research to investigate enzyme interactions or as a fluorescent tag precursor due to the inherent properties of the coumarin core.

Basic Information

Product Name	(+)-6-(3-Chloro-2-Hydroxy-3-Methylbutyl)-5,7-Dimethoxycoumarin
CAS No.	15575-50-5
Molecular Formula	C₁₆H₁₉ClO₅
Molecular Weight	326.77 g/mol
Synonyms	(+)-6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxy-2H-chromen-2-one; 6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxycoumarin; 5,7-Dimethoxy-6-(3-chloro-2-hydroxy-3-methylbutyl)coumarin; NSC 339586; Aurantiamide acetate impurity C; A related compound of Scoparone.
EINECS	Contact for details

Quality Control

Every batch of (+)-6-(3-Chloro-2-Hydroxy-3-Methylbutyl)-5,7-Dimethoxycoumarin is produced and tested under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing full traceability and detailed analytical results from techniques including HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Optical Rotation [α]₂₀D	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.