Description

S-Tritylcysteamine Hydrochloride is a protected thiol reagent and a key intermediate in organic synthesis and peptide chemistry. Its primary value lies in its ability to introduce a protected cysteine moiety, which is crucial for the controlled formation of disulfide bonds in complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of peptide-based therapeutics and for use in chemical biology studies.

Application

• Peptide Synthesis: As a crucial building block for introducing protected cysteine residues during solid-phase or solution-phase peptide synthesis.
• Chemical Biology & Bioconjugation: Used to modify proteins, antibodies, or other biomolecules via thiol-reactive chemistry after deprotection.
• Pharmaceutical Intermediates: Serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) that contain disulfide bridges or require thiol protection strategies.
• Ligand & Probe Development: Employed in the creation of molecular probes, enzyme inhibitors, and other bioactive compounds where a protected thiol group is required for further functionalization.
• Material Science: Can be used to functionalize surfaces or polymers by providing a protected thiol handle for subsequent chemistry.

Basic Information

Product Name	S-Tritylcysteamine Hydrochloride
CAS No.	15297-43-5
Molecular Formula	C21H22ClNS
Molecular Weight	355.92 g/mol
Synonyms	2-[(Triphenylmethyl)thio]ethanamine Hydrochloride; 2-(Tritylthio)ethylamine Hydrochloride; NSC 328786; Cysteamine, S-trityl-, hydrochloride; Trityl-cysteamine HCl; S-Trityl-2-aminoethanethiol Hydrochloride; S-Trityl-2-mercaptoethylamine Hydrochloride
EINECS	Contact for details

Quality Control

Our S-Tritylcysteamine Hydrochloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.