Description

Ethylenediaminetetraacetic Acid-D4 (Carb CAS NO 15251-22-6 is a deuterated analog of the classic chelating agent EDTA, where four hydrogen atoms are replaced by deuterium. This isotopic labeling is critical for applications requiring high analytical precision and stability, such as internal standards in mass spectrometry. It is an essential reagent for researchers and manufacturers in the pharmaceutical, analytical chemistry, and environmental testing sectors who require traceable and interference-free quantification of metal ions.

Application

• Internal Standard for Quantitative Analysis: Serves as a stable, non-interfering internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of EDTA and related chelators.
• Pharmaceutical Research & Development: Used in pharmacokinetic and metabolic stability studies of chelation therapies, providing a reliable isotopic reference for tracking drug disposition.
• Environmental & Food Safety Testing: Enables precise measurement of EDTA and metal-EDTA complexes in complex matrices like water, soil, and food products for regulatory compliance.
• NMR Spectroscopy: Functions as a deuterated shift reagent or a tool for studying metal-binding kinetics in deuterated solvents without proton interference.
• Isotope Dilution Mass Spectrometry (IDMS): A primary standard for high-accuracy, definitive methods in clinical and forensic laboratories.
• Chemical Mechanism Studies: Utilized to elucidate reaction pathways and binding constants in deuterated environments for fundamental chelation chemistry research.

Basic Information

Product Name	Ethylenediaminetetraacetic Acid-D4 (Carb CAS NO 15251-22-6
CAS No.	15251-22-6
Molecular Formula	C10H12D4N2O8
Molecular Weight	296.27 g/mol
Synonyms	EDTA-d4; Deuterated EDTA; (Carboxy-d2methyl)deuterated EDTA; Ethylenedinitrilotetraacetic Acid-d4; Edetic Acid-d4; 2,2',2'',2'''-(Ethane-1,2-diyldinitrilo)tetraacetic-d4 acid; N,N'-1,2-Ethanediylbis[N-(carboxymethyl)glycine]-d4; Versene Acid-d4
EINECS	Contact for details

Quality Control

Our Ethylenediaminetetraacetic Acid-D4 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and Mass Spectrometry to confirm isotopic purity and chemical identity, and HPLC to determine chemical purity. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes batch-specific data on assay, isotopic enrichment, and impurity profiles to ensure it meets the stringent requirements for analytical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D
Assay (HPLC)	≥ 98.0%
Heavy Metals	≤ 10 ppm
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.