Description

3-(1H-Indol-3-Yl)-2-Methyl-Propionic Acid is a high-purity indole derivative that serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique structure, featuring both an indole ring and a carboxylic acid group, makes it invaluable for constructing complex molecules with specific stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, especially those targeting neurological and metabolic pathways.
• Agrochemical Research: Used in the development of new plant growth regulators and pesticides with specific modes of action.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and as a probe for investigating biological pathways.
• Organic Synthesis: A versatile building block for constructing complex heterocyclic compounds, natural product analogs, and specialty chemicals.
• Material Science: Potential monomer or additive in the research of advanced polymeric materials with specific optical or electronic properties.

Basic Information

Product Name	3-(1H-Indol-3-Yl)-2-Methyl-Propionic Acid
CAS No.	15142-91-3
Molecular Formula	C₁₂H₁₃NO₂
Molecular Weight	203.24 g/mol
Synonyms	2-Methyl-3-(1H-indol-3-yl)propanoic acid; 2-Methyl-3-indol-3-ylpropionic acid; (RS)-2-Methyl-3-(1H-indol-3-yl)propionic acid; (±)-2-Methyl-3-(1H-indol-3-yl)propionic acid; 3-Indol-3-yl-2-methylpropionic acid; DL-2-Methyl-3-(3-indolyl)propionic acid; β-Methyl-3-indolepropionic acid; 15142-91-3
EINECS	Contact for details

Quality Control

Our 3-(1H-Indol-3-Yl)-2-Methyl-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.