Description

4-Fluoro-3-Nitrobenzyl Bromide is a versatile and highly reactive halogenated aromatic building block. This compound is essential for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research, where its bromomethyl and nitro groups serve as key handles for further functionalization. It is primarily sought after by R&D chemists and process development scientists in the life sciences and advanced materials sectors for constructing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing benzylamine or heterocyclic motifs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, leveraging its halogen and nitro substituents for structural diversity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its aromatic core and reactive sites.
• Peptide Mimetics and Bioconjugation: The reactive benzyl bromide group is useful for alkylation reactions in creating peptide analogs or for bioconjugation linkers.
• Chemical Biology Probes: Acts as a scaffold for developing fluorescent probes or affinity tags to study biological processes.

Basic Information

Product Name	4-Fluoro-3-Nitrobenzyl Bromide
CAS No.	15017-52-4
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	1-(Bromomethyl)-4-fluoro-3-nitrobenzene; α-Bromo-4-fluoro-3-nitrotoluene; (4-Fluoro-3-nitrophenyl)methyl bromide; 3-Nitro-4-fluorobenzyl bromide; 4-Fluoro-3-nitrobenzylbromide; 4-Fluoro-3-nitro-α-bromotoluene; NSC 403824
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Nitrobenzyl Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactivity, it is recommended to handle under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	65 - 68 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.