Description

n-[2-Hydroxy-5-[1-Hydroxy-2-(Isopropylamino)Ethyl]Phenyl]Methanesulphonamide Monohydrochloride is a high-purity, pharmacologically active compound primarily utilized as a key intermediate in advanced pharmaceutical synthesis. Its molecular structure is integral to the development of specific β-adrenergic receptor ligands. This compound is essential for research and development laboratories and production facilities focused on cardiovascular and respiratory therapeutics. We supply this material with a commitment to stringent quality control and reliable global logistics.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of selective β-1 adrenergic receptor antagonists (β-blockers).
• Active Pharmaceutical Ingredient (API) Development: Used in research for developing new chemical entities targeting cardiovascular diseases.
• Biochemical Research: Employed in pharmacological studies to investigate adrenergic receptor mechanisms and signal transduction pathways.
• Reference Standard: Functions as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial manufacturing of related drug substances.

Basic Information

Product Name	n-[2-Hydroxy-5-[1-Hydroxy-2-(Isopropylamino)Ethyl]Phenyl]Methanesulphonamide Monohydrochloride
CAS No.	14816-67-2
Molecular Formula	C13H23N2O4S•HCl
Molecular Weight	338.86 g/mol
Synonyms	1-(4-Hydroxy-3-((methylsulfonyl)amino)phenoxy)-3-((1-methylethyl)amino)-2-propanol hydrochloride; Betaxolol Impurity B (Hydrochloride); Betaxolol Related Compound B; (RS)-1-[4-[2-(Isopropylamino)-1-hydroxyethyl]phenoxy]-3-(methylsulfonamido)propan-2-ol Hydrochloride; LK 261-126; LK-261-126; LK261126; 1-(4-Hydroxy-3-(N-methylsulfamoyl)phenoxy)-3-isopropylaminopropan-2-ol Hydrochloride
EINECS	Contact for details

Quality Control

Our n-[2-Hydroxy-5-[1-Hydroxy-2-(Isopropylamino)Ethyl]Phenyl]Methanesulphonamide Monohydrochloride is manufactured under a quality management system and undergoes rigorous analytical testing. Each batch is released with a comprehensive Certificate of Analysis (COA) that confirms identity, purity, and conformance to specifications. We can supply material suitable for use under cGMP guidelines for pharmaceutical R&D. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.