Description

(3Ar,4S,7R,7As) 4,7-Methano-1H-Isoindole-1,3(2H)-Dione is a high-purity, stereochemically defined bicyclic imide derivative. This compound serves as a critical chiral building block and advanced intermediate in sophisticated organic synthesis. It is essential for research and development in the pharmaceutical and agrochemical industries, where precise molecular architecture is required. Its unique bridged structure offers valuable rigidity and functional handles for constructing complex active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific stereochemistry for optimal activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new reaction methodologies and complex natural product synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, specialty fine chemicals and dyes.

Basic Information

Product Name	(3Ar,4S,7R,7As) 4,7-Methano-1H-Isoindole-1,3(2H)-Dione
CAS No.	14805-29-9
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	(3aR,4S,7R,7aS)-4,7-Methanoisobenzofuran-1,3-dione; (3aR,4S,7R,7aS)-Hexahydro-4,7-methanoisobenzofuran-1,3-dione; (3aR,4S,7R,7aS)-3a,4,7,7a-Tetrahydro-4,7-methanoisobenzofuran-1,3-dione; endo-Norborn-5-ene-2,3-dicarboximide; endo-5-Norbornene-2,3-dicarboximide; endo-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboximide; Chiral Norbornene Imide
EINECS	Contact for details

Quality Control

Our (3Ar,4S,7R,7As) 4,7-Methano-1H-Isoindole-1,3(2H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.