Description

2,3,5,6-Tetramethylbenzenethiol is a specialized organosulfur compound featuring a sterically hindered thiol group on a heavily substituted benzene ring. This unique structure makes it a valuable building block and ligand precursor in advanced organic synthesis and materials science. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of novel drug candidates, particularly in creating sulfur-containing heterocycles or as a ligand precursor for metal-catalyzed coupling reactions.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the tetramethyl-substituted thiol moiety can impart specific biological activity and stability.
• Ligand in Catalysis: Acts as a precursor for the synthesis of sterically demanding thiolate ligands used in homogeneous catalysis for fine chemical and polymer production.
• Polymer Modification: Employed as a chain-transfer agent or functional monomer in the synthesis of specialty polymers to introduce sulfur functionalities or control molecular weight.
• Material Science Research: Utilized in the development of self-assembled monolayers (SAMs) on metal surfaces and in the creation of novel organic electronic materials.
• Chemical Synthesis Reagent: Functions as a nucleophile or a protecting group in complex multi-step organic syntheses due to its reactivity and steric profile.

Basic Information

Product Name	2,3,5,6-Tetramethylbenzenethiol
CAS No.	14786-84-6
Molecular Formula	C10H14S
Molecular Weight	166.28 g/mol
Synonyms	2,3,5,6-Tetramethylbenzenethiol; 2,3,5,6-Tetramethylthiophenol; Durenethiol; 2,3,5,6-Tetramethylphenyl mercaptan; 1,2,4,5-Tetramethyl-6-mercaptobenzene; Thiodurene; Durene-2-thiol; 6-Mercaptodurene
EINECS	Contact for details

Quality Control

Our 2,3,5,6-Tetramethylbenzenethiol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee reliable and reproducible performance in your processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is easily oxidized (store under inert atmosphere).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.