Description

Acetyl Chloride-2-13C is a stable isotope-labeled derivative of acetyl chloride, where the carbonyl carbon is enriched with the carbon-13 isotope. This compound is a critical reagent for advanced research and analytical applications requiring precise molecular tracing. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for metabolic studies, reaction mechanism elucidation, and as an internal standard in quantitative mass spectrometry.

Application

• Isotope-Labeled Synthesis: Acts as a key carbon-13 labeled building block for the synthesis of complex molecules in pharmaceutical and agrochemical research.
• Metabolic Pathway Tracing: Used in NMR and Mass Spectrometry studies to track the incorporation and fate of specific carbon atoms in biological systems.
• Internal Standard for Quantitation: Serves as a high-purity internal standard in LC-MS and GC-MS analyses to ensure accurate quantification of acetyl chloride or related compounds.
• Mechanistic Studies: Employed in organic chemistry research to investigate reaction mechanisms, particularly acylation reactions, via isotopic labeling.
• Production of Labeled Fine Chemicals: Used in the manufacture of other carbon-13 labeled intermediates for diagnostic imaging agents and advanced materials.

Basic Information

Item	Detail
Product Name	Acetyl Chloride-2-13C
CAS No.	14770-40-2
Molecular Formula	13CCH3ClO
Molecular Weight	79.48 g/mol
Synonyms	Acetic-2-13C chloride; Ethanoyl-2-13C chloride; [2-13C]Acetyl chloride; 13C-Labeled acetyl chloride; Carbon-13 labeled acetyl chloride; 13C-AcCl; Isotopic acetyl chloride; 13C Carbonyl acetyl chloride
EINECS	Contact for details

Quality Control

Our Acetyl Chloride-2-13C is produced under stringent conditions to ensure exceptional isotopic and chemical purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and impurity profiles via validated analytical methods including NMR, GC-MS, and titration. We adhere to cGMP principles for consistent quality, meeting the exacting standards required for research and commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C to maintain stability and isotopic integrity. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Isotopic Enrichment (13C)	≥ 99 atom %
Chemical Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.