Description

2,2,5,5-Tetramethyl-1,3-Dioxa-2-Silacyclohexane is a specialized organosilicon compound featuring a cyclic siloxane-acetal structure. This chemical is valued for its role as a versatile silylating agent and protecting group precursor in advanced synthetic chemistry. It is primarily needed by manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex molecules and functional materials.

Application

• Pharmaceutical Intermediate Synthesis: Used as a protecting group for diols and polyols in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Production: Serves as a key building block in the manufacture of advanced pesticides and herbicides requiring specific stereochemistry.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating novel silicone-based polymers with tailored properties.
• Surface Modification: Employed to derivatize silica and other metal oxide surfaces, altering their hydrophobicity and reactivity.
• Organic Synthesis Reagent: Functions as a silylating agent to introduce the tetramethyl-1,3-dioxa-2-silacyclohexane moiety into target molecules.
• Laboratory Research: Utilized in academic and industrial R&D for developing new synthetic methodologies and catalytic processes.

Basic Information

Product Name	2,2,5,5-Tetramethyl-1,3-Dioxa-2-Silacyclohexane
CAS No.	14760-11-3
Molecular Formula	C7H16O2Si
Molecular Weight	160.29 g/mol
Synonyms	1,3-Dioxa-2-silacyclohexane, 2,2,5,5-tetramethyl-; Tetramethyl-1,3-dioxa-2-silacyclohexane; 2,2,5,5-Tetramethyl-2-sila-1,3-dioxacyclohexane; Acetaldehyde Tetramethylsilyl Acetal; (Tetramethyl-1,3-dioxa-2-silacyclohexane); Acetaldehyde O,O'-(tetramethylsilylene) acetal; TMDS (context-specific abbreviation).
EINECS	238-828-5

Quality Control

Our 2,2,5,5-Tetramethyl-1,3-Dioxa-2-Silacyclohexane is produced under strict quality management systems. Every batch undergoes rigorous analytical testing including GC, NMR, and Karl Fischer titration to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.410 - 1.415
Density (20°C)	0.92 - 0.96 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.