Description

2-(Chloromethyl)-6-Nitro-1H-Benzo[D]Imidazole is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its bifunctional reactivity, featuring both an electrophilic chloromethyl group and an electron-deficient nitro-substituted benzimidazole ring, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, serving as a key precursor for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel benzimidazole-based therapeutic agents, including potential antivirals, antifungals, and anticancer compounds.
• Agrochemical Synthesis: Used in the development of next-generation fungicides and herbicides, leveraging the bioactive benzimidazole scaffold.
• Material Science Research: Serves as a building block for creating specialized polymers, ligands for metal-organic frameworks (MOFs), and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design of activity-based probes (ABPs) and affinity tags due to its reactive chloromethyl handle.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing complex heterocyclic dyes and colorants.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis and scale-up projects under cGMP or ISO standards.

Basic Information

Product Name	2-(Chloromethyl)-6-Nitro-1H-Benzo[D]Imidazole
CAS No.	14625-39-9
Molecular Formula	C8H6ClN3O2
Molecular Weight	211.61 g/mol
Synonyms	6-Nitro-2-(chloromethyl)-1H-benzimidazole; 2-Chloromethyl-6-nitrobenzimidazole; 1H-Benzimidazole, 2-(chloromethyl)-6-nitro-; 2-(Chloromethyl)-6-nitro-1H-benzimidazole; NSC 403697; 6-Nitro-2-chloromethylbenzimidazole; 2-(Chloromethyl)-6-nitrobenzimidazole
EINECS	Contact for details

Quality Control

Every batch of 2-(Chloromethyl)-6-Nitro-1H-Benzo[D]Imidazole is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom specifications for research or cGMP applications can be supported upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark cabinet. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.