Description

3-Bromo-1H-Pyrazole is a versatile brominated heterocyclic building block essential for modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediates: A key synthon for the synthesis of drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the production of modern fungicides, herbicides, and insecticides that require specific pyrazole-based scaffolds.
• Material Science Research: Serves as a precursor for functionalized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for activity-based probes and molecular tags.
• Cross-Coupling Reactions: Acts as a pivotal substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to form complex biaryl structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial research quantities.

Basic Information

Product Name	3-Bromo-1H-Pyrazole
CAS No.	14521-80-3
Molecular Formula	C3H3BrN2
Molecular Weight	146.97 g/mol
Synonyms	3-Bromopyrazole; 1H-Pyrazole, 3-bromo-; 3-Bromo-1H-pyrazole; Pyrazole, 3-bromo-; NSC 403119; 3-Br-Pyrazole; 3-Bromo-pyrazole; 3-Brom-1H-pyrazol
EINECS	Contact for details

Quality Control

Our 3-Bromo-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.