Description

6-Hydroxyestriol is a hydroxylated metabolite of the endogenous estrogen, estriol. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in estrogen metabolism and potential biological activity. It serves as a critical reference standard and intermediate for researchers and manufacturers in the life sciences sector. Key applications include use as a biomarker in clinical studies and as a building block for synthesizing more complex steroid derivatives.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments and the validation of methods in drug development and quality control laboratories.
• Biochemical Research: Employed in studies investigating estrogen metabolism, receptor binding affinity, and hormonal pathways.
• Diagnostic Reagent Manufacturing: Serves as a key component in the production of immunoassay kits for measuring estrogen metabolites in clinical samples.
• Academic Research: Utilized in university and institutional labs for metabolic profiling and endocrinology research projects.
• Metabolite Synthesis: Acts as a precursor or intermediate in the organic synthesis of novel steroid-based compounds for therapeutic evaluation.

Basic Information

Product Name	6-Hydroxyestriol
CAS No.	14507-00-7
Molecular Formula	C18H24O5
Molecular Weight	320.38 g/mol
Synonyms	Estra-1,3,5(10)-triene-3,6,16α,17β-tetrol; 6,16α,17β-Trihydroxyestra-1,3,5(10)-trien-3-ol; 6-OH-Estriol; 6-Hydroxy-Oestriol; 6α-Hydroxyestriol
EINECS	Contact for details

Quality Control

Our 6-Hydroxyestriol is produced under a rigorous quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.