Description

2-(Chlorodifluoromethyl)-1H-Benzimidazole is a specialized fluorinated benzimidazole derivative, a key heterocyclic building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the chlorodifluoromethyl group, making it a versatile precursor for introducing fluorinated motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, especially those targeting enzyme inhibition where the benzimidazole core is pharmacologically active.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorination often enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced materials with specific electronic or surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a scaffold for constructing complex heterocyclic compounds in academic and industrial R&D settings.
• Fluorine Chemistry Studies: A valuable compound for investigating the synthesis and reactivity of organofluorine compounds, a key area in modern chemistry.

Basic Information

Product Name	2-(Chlorodifluoromethyl)-1H-Benzimidazole
CAS No.	14468-38-3
Molecular Formula	C8H5ClF2N2
Molecular Weight	202.59 g/mol
Synonyms	2-(Chlorodifluoromethyl)-1H-benzimidazole; 1H-Benzimidazole, 2-(chlorodifluoromethyl)-; 2-(Chlorodifluoromethyl)benzimidazole; 2-(Chlorodifluoromethyl)-1H-benzo[d]imidazole; Benzimidazole, 2-(chlorodifluoromethyl)-; α,α-Difluoro-α-chloromethylbenzimidazole
EINECS	Contact for details

Quality Control

Our 2-(Chlorodifluoromethyl)-1H-Benzimidazole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.