Description

2,2-Dimethyl-4(R)-4-Bromomethyl-1,3-Dioxalane is a high-purity chiral synthon and versatile alkylating agent, valued for its role in stereoselective synthesis. This compound is critical for constructing complex molecular architectures with precise stereochemical control. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug molecules, particularly in antiviral, anticancer, and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as an alkylating agent in stereocontrolled reactions to introduce chiral centers with high enantiomeric purity.
• Nucleoside & Nucleotide Chemistry: Serves as a protected glycosyl donor or a precursor for modified sugar moieties in nucleoside analog development.
• Ligand & Catalyst Preparation: Employed in the synthesis of chiral ligands and organocatalysts for use in homogeneous catalysis.
• Polymer Science: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Agrochemical Research: Utilized in the development of chiral active ingredients for herbicides, fungicides, and pesticides.

Basic Information

Product Name	2,2-Dimethyl-4(R)-4-Bromomethyl-1,3-Dioxalane
CAS No.	14437-87-7
Molecular Formula	C6H11BrO2
Molecular Weight	195.06 g/mol
Synonyms	(R)-4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane; (4R)-4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane; 4(R)-Bromomethyl-2,2-dimethyl-1,3-dioxolane; D-4-Bromomethyl-2,2-dimethyl-1,3-dioxolane; (R)-(-)-4-Bromomethyl-2,2-dimethyl-1,3-dioxolane; (R)-2,2-Dimethyl-4-bromomethyl-1,3-dioxolane; Bromomethyl acetonide (R-isomer)
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-4(R)-4-Bromomethyl-1,3-Dioxalane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.