Description

1-(2-Aminoethyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline Dihydrochloride is a high-purity, pharmaceutically relevant organic salt. This compound serves as a critical building block (API intermediate) in the synthesis of complex molecules, valued for its defined stereochemistry and reactivity. It is primarily sought by pharmaceutical R&D and fine chemical manufacturers for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of alkaloid-derived active pharmaceutical ingredients (APIs).
• Neurological Research: Building block for compounds targeting neurotransmitter systems and central nervous system disorders.
• Cardiovascular Drug Development: Intermediate for potential vasodilatory or antihypertensive agents.
• Chemical Synthesis: Versatile chiral synthon for constructing complex tetrahydroisoquinoline scaffolds in medicinal chemistry.
• Reference Standard: High-purity material for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	1-(2-Aminoethyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline Dihydrochloride
CAS No.	14421-47-7
Molecular Formula	C₁₃H₂₂Cl₂N₂O₂
Molecular Weight	309.23 g/mol
Synonyms	6,7-Dimethoxy-1,2,3,4-tetrahydro-1-(2-aminoethyl)isoquinoline Dihydrochloride; 1-(2-Aminoethyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline Hydrochloride (1:2); 6,7-Dimethoxy-2-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-ium Chloride (related); TIQ Amine Dihydrochloride Derivative; NSC 113927; 2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)ethan-1-amine Dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Aminoethyl)-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline Dihydrochloride is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.