Description

β-Alanine-β-14C is a carbon-14 radiolabeled isotopologue of the non-essential amino acid β-alanine, specifically labeled at the beta carbon position. This compound is a critical tool for metabolic and pharmacokinetic studies, enabling researchers to precisely track the absorption, distribution, metabolism, and excretion (ADME) of β-alanine and related compounds. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in advanced tracer studies and drug development programs.

Application

• Metabolic Pathway Tracing: Used as a radioactive tracer to study the metabolic fate of β-alanine in biological systems.
• Pharmacokinetic (PK) Studies: Essential for quantitative ADME studies in preclinical drug development to understand the body's processing of β-alanine or β-alanine-containing compounds.
• Biochemical Research: Investigates the role of β-alanine in the synthesis of carnosine and other peptides within muscular and neurological tissues.
• Drug Development Support: Aids in the development and validation of analytical methods (e.g., LC-MS, scintillation counting) for detecting β-alanine and its metabolites.
• Nutritional Science Studies: Applied in research examining the uptake and utilization of β-alanine as a dietary supplement for athletic performance.

Basic Information

Product Name	β-Alanine-β-14C
CAS No.	14405-06-2
Molecular Formula	C3H714CNO2
Molecular Weight	Contact for details
Synonyms	3-Aminopropanoic acid-3-14C; β-Alanine-3-14C; 3-14C-β-Alanine; Abufene-14C (labeled); (3-14C)-3-Aminopropionic Acid; β-14C-Aminopropionic Acid; NSC 8366-14C; 14C-Labeled β-Alanine
EINECS	Contact for details

Quality Control

Every batch of β-Alanine-β-14C is manufactured and analyzed under strict quality systems to ensure traceability, purity, and specific activity consistency. Our products undergo rigorous quality testing, including radiochemical purity analysis by HPLC, to ensure compliance with the stringent requirements of research applications. Certificates of Analysis (COA) detailing specific activity, purity, and solvent composition are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at recommended temperatures (typically 2-8°C or as specified on the label). Due to its hygroscopic (moisture-sensitive) nature, the material should be handled in a controlled environment to prevent moisture uptake. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 98%
Chemical Purity (HPLC)	≥ 95%
Specific Activity	Customizable (mCi/mmol)
Solvent (if supplied as solution)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.