Description

2-(But-3-Yn-2-Yl)Isoindoline-1,3-Dione (CAS NO 14396-89-5) is a specialized organic building block featuring a phthalimide core linked to an alkyne-functionalized butyl chain. This compound matters as a versatile intermediate for advanced organic synthesis, enabling the construction of complex molecular architectures through click chemistry and cross-coupling reactions. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of new drug candidates, particularly for introducing alkyne handles for bioconjugation.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structure can be incorporated into bioactive molecules.
• Material Science Research: Acts as a monomer or precursor for synthesizing specialty polymers, dendrimers, and other functional organic materials.
• Click Chemistry Substrate: The terminal alkyne group makes it an ideal participant in Huisgen cycloaddition (copper-catalyzed azide-alkyne cycloaddition) reactions for labeling and ligation.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for metal catalysis or as a scaffold in organocatalysis research.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new reaction methodologies and complex molecule construction.

Basic Information

Product Name	2-(But-3-Yn-2-Yl)Isoindoline-1,3-Dione
CAS No.	14396-89-5
Molecular Formula	C₁₂H₉NO₂
Molecular Weight	199.21 g/mol
Synonyms	2-(3-Butyn-2-yl)isoindoline-1,3-dione; 2-(But-3-yn-2-yl)-1H-isoindole-1,3(2H)-dione; 2-(1-Methyl-2-propynyl)phthalimide; 2-(1-Methyl-2-propynyl)-1H-isoindole-1,3(2H)-dione; N-(1-Methyl-2-propynyl)phthalimide; 2-(But-3-yn-2-yl)phthalimide; 14396-89-5
EINECS	Contact for details

Quality Control

Our 2-(But-3-Yn-2-Yl)Isoindoline-1,3-Dione is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and meet the stringent requirements of our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.